This is the comprehensively revised and updated edition of the book, with the inclusion of new chapters in emerging areas such as palliative nephrology, a subject of increasing importance in view of the rising burden of kidney diseases, now recognized as a major component of ?lifestyle diseases?. The third edition of the book was widely appreciated, particularly by practitioners, physicians and residents preparing for a career in nephrology for its simple presentation and elegant discussion. In view of the rapid advances in the field, the preparation of a new edition after 5 years became a necessity. Prof R Kasi Visweswaran has brought together contributions from highly experienced faculty members representing national institutes, medical colleges and leading teaching hospitals across India, ensuring breadth and depth of expertise. Key Features ? Written in a simple language with a clear narrative style for ease of understanding ? Coverage of fundamental concepts as the basis for clinical practice ? Introduction to molecular biology and genetics in nephrology ? Comprehensive discussion of clinical features, investigations and management ? Practical approach to common nephrological problems ? Dedicated chapters on detailed interpretation of individual electrolyte and acid?base disorders ? Well-illustrated with figures and tables for clarity