Python is the leading language of our time which finds applications in every aspect of life involving technology. This book containing 17 chapters,written with lucid language for students and general readers,follows a step by step approach on the introduction to and applications of Python computing. The chapters are broadly classified into core Python and Computations with external Python packages (e.g, NumPy, SciPy, Matplotlib, Pandas, SymPy, tkinter). Plenty of examples applications and graphical demonstrations will enable the readers to learn the fundamentals of Python easily and develop problem solving skill on their own.