This course is designed to convey the knowledge necessary to understand issues related to Advanced Spectral Analysis. Advanced Spectral Analysis includes the various hyphenated analytical instrumental techniques for identification, characterization and quantification of drugs. Instruments dealt are LC-MS, GC-MS, ATR-IR, DSC etc. The Objectives of this book is upon completion of this course the student should be able to understand: 1) Interpretation of the NMR, Mass and IR spectra of various organic compounds 2) Theoretical and practical skills of the hyphenated instruments 3) Identification of organic compounds The book is designed according to the curriculum of postgraduate course of Pharmaceutical Chemistry in pharmacy by Pharmacy Council of India new syllabus useful all over India. After completion of each chapter revision points and important questions are included.