This book is the result of author's over 30 years of teaching and collaboration with graduate students across multiple universities. Medicinal chemistry is a vital discipline in drug discovery and development (DDD), bridging various scientific fields such as biology, toxicology, pharmacology, and more. The positive feedback on the previous works has inspired the authors to create this comprehensive yet accessible resource. Designed for undergraduate students preparing for Medicinal Chemistry II, this volume follows the revised syllabus of the Pharmacy Council of India. It consists of thirteen chapters covering topics such as antihistamines, anticancer agents and diuretics among others. Each chapter includes an introduction, classification, structure?activity relationship (SAR), drug structures, IUPAC names, mechanisms of action, uses and synthesis all aimed at enhancing student understanding.